이진구 사진

이진구 | 의과대학 의예과

  • 직급:
    연구전담조교수

소개

연구 분야
1. 노화 및 파킨슨병 동물모델을 이용하여 장기간 전자파 노출이 퇴행성 뇌질환 발생에 미치는 영향 연구
2. 만성 스트레스 자극에의한 뇌 신경 세포 사멸 연구 (구금 또는 전자파 스트레스 모델을 이용하여 뇌 내 모노아민의 변화 및 행동 반응 연구)
3. 천연물 유래 신경병증성 통증 치료 후보물질 발굴 및 통증 제어 기전 연구

학력

  • [2002] 박사 한림대학교 의학과 분자신경약리학

주요연구분야

만성 스트레스
신경면역조절
신경병증성통증
패혈증
전자파의 생체 영향

컨설팅 가능 분야

중추신경약리
통증전달
퇴행성 뇌질환 (PD, AD)
신경세포사멸
전자파의 생체 영향

연구업적

  • 일반논문[20170901] The distribution of calbindin-D28k, parvalbumin, and calretinin immunoreactivity in the inferior colliculus of circling mouse
  • 일반논문[20161101] 선진 외국의 동물대체시험법 개발현황과 전망
  • 일반논문[20160501] Characterization of temporal expressions of FOXO and pFOXO proteins in the hippocampus by kainic acid in mice: involvement of NMDA and non-NMDA receptors
  • 일반논문[20150105] Methyl gallate from Acer barbinerve decreases melanin synthesis in Mel-Ab cells
  • 일반논문[20141001] Role of corticotropin-releasing hormone receptor 1 in the regulation of nociception in mice
  • 일반논문[20140901] Pertussis Toxin Administered Spinally Induces a Hypoglycemic Effect on Normal and Diabetic Mice
  • 일반논문[20140430] Alteration of Striatal Tetrahydrobiopterin in Iron-Induced Unilateral Model of Parkinson’s Disease
  • 일반논문[20140401] Temporal expression of hippocampal lysophosphatidic acid receptors and their roles in kainic acid-induced neurotoxicity
  • 일반논문[20131101] Deficiency of alpha-calcitonin gene-related peptide induces inflammatory responses and lethality in sepsis
  • 일반논문[20131031] Antinociceptive effect of glyasperin F isolated from Glycyrrhiza inflata in mice
  • 일반논문[20131030] Anti-depressant like effect of methyl gallate isolated from Acer barbinerve in mice
  • 일반논문[20130801] Neuroprotective effect of ginseng against alteration of calcium binding proteins immunoreactivity in the mice hippocampus after radiofrequency exposure
  • 일반논문[20130401] Role of α-CGRP in the regulation of neurotoxic responses induced by kainic acid in mice
  • 일반논문[20130217] Differential Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine on Motor Behavior and Dopamine Levels at Brain Regions in Three Different Mouse Strains
  • 일반논문[20120424] Effect of Agrimonia pilosa Ledeb Extract on the Antinociception and Mechanisms in Mouse
  • 일반논문[20120201] Antinociceptive profiles and mechanisms of orally administered curcumin in various pain models
  • 일반논문[20111101] Antinociceptive profiles and mechanisms of orally administered Aster Koraiensis extract in the mouse
  • 일반논문[20111001] Lactosylceramide Mediates the Expression of Adhesion Molecules in TNF- alpha and IFN gamma-stimulated Primary Cultured Astrocytes
  • 학술발표[20131101] Effects of bromocriptine and L-DOPA on motor behaviors of hLRRK2 (G2019S) transgenic mice
  • 학술발표[20131101] Differential effects of MPTP on motpr behavior and dopamine levels at brain regions in different mouse strains
  • 학술발표[20131031] Anti-depressant like effect of methyl gallate isolated from Acer barbinerve in mice
  • 학술발표[20130829] 835 MHz의 전자기장에 노출된 생쥐의 신경전달물질과 행동반응 분석
  • 학술발표[20130319] Analysis of tetrahydrobiopterin and neurotransmitters in mouse brain subjected to repeated restraint stress
  • 학술발표[20121216] Analysis of Neurotransmitters and Behavioral Responses in 835 MHZ Radiofrequency Exposed Mice
  • 학술발표[20121101] Differential effects of MPTP on motor behavior and Dopamine levels at brain regions in mouse
  • 학술발표[20121005] Antinociceptive effect of glyasperin F isolated from Glycyrrhiza inflata
  • 학술발표[20120420] Determining neurotransmitters of mouse brain sections following exposure to 835 MHz radiofrequency by using liquid chromatography coupled electrospary tandem mass spectrometry.
  • 학술발표[20111112] Effect of intrathecally administered cholera toxin in sepsis-induced hypoglycemia
  • 학술발표[20111104] Expression of FoxO3a in Kainic acid-induced Hippocampal Cell Death
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