김희정 사진

김희정 | 의과대학 의예과

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소개

신경퇴행과정(neurodegenerative processes)에 관심을 갖고 연구하고 있습니다. 퇴행성 신경질환의 초기에 발생되는 시냅스 손상은 HIV-1 관련 치매(HIV-1 associated dementia)나 알츠하이머병(Alzheimer’ disease)을 겪는 환자에서 인지능력이 감퇴되는 현상과 잘 연관되어 있으며, 신경독성에 의한 시냅스 기능 상의 변화를 연구하는 데 유용한 실험법을 고안하였습니다. 여러 논문들을 통해서 시냅스 손상이 세포 사멸 과정에서 발생되는 초기 현상이 아니라 과도한 흥분성 자극으로 부터 세포를 보호할 수 있는 독립적 기전임을 발표한 바 있습니다. 앞으로 진행할 후속연구들은 시냅스 접점수의 변화가 정서장애로부터의 안정을 유도하는 데 기반이 되는 기전을 알아보고, 퇴행성 신경질환을 보호, 치료할 수 있는 방법을 모색하는 데 그 목적을 두고 진행하고자 합니다.

학력

  • [1999] 학사 경북대학교 생명과학부 미생물학전공
  • [2001] 석사 경북대학교(의,치대) 의학과 생리학전공
  • [2005] 박사 가톨릭대학교(성의교정) 의학과 생리학전공

주요경력

  • 가톨릭대학교 의과대학 (2001-01-01)
  • University of Minnesota Medical School (2005-03-01)
  • University of Minnesota Medical School (2009-10-19)

주요연구분야

Drug Abuse
Glial-Neuronal Signaling mechanisms
Neurodegnerative diseases
Neuroprotective mechanism
Regulation of synaptogenesis and synaptic transmission

컨설팅 가능 분야

Neurophysiology, Neurodegenerative diseases (dementia), Synapse, Neurotoxicity

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