박정수 사진

박정수 | 의과대학 의예과

  • 직급:
    교수

소개

의예과와 의학과의 분자생물학, 유전학, 생화학 및 실습, 신호전달 생화학 등의 강의를 담당하고 있다. 연구분야는 노화과정에서 나타나는 여러가지 기능 저하의 기전을 연구하고 있는데, 이를 통해 노인성 질병의 예방, 최적의 기능 유지를 통한 건강한 노화를 가능하게 하는 것을 종국의 목표로 하여 다양한 분야의 연구를 진행하고 있다.
- Functional alteration of senescent fibroblasts
- Cellular senescence of mesenchymal stem cells
- Change of neurogenesis in aged brain
- Change of signaling events in neural precursor cells during ageing

학력

  • [1998] 석사 서울대학교 생화학
  • [2000] 박사 서울대학교 생화학 생화학

주요연구분야

Aging and differentiation of mesenchymal stem cells
Antiaging strategy
Basic mechanism of ageing
Cellular Senescence
Signaling of aged neural precursor cells

컨설팅 가능 분야

Cellular Senescence
Endocytosis
Signal Transduction

연구업적

  • 일반논문[20150701] beta 2-microglobulin is a systemic pro-aging factor that impairs cognitive function and neurogenesis
  • 일반논문[20130915] Inhibition of Nitric Oxide Mediated Protein Nitration Therapeutic Implications in Experimental Radiculopathy
  • 일반논문[20111230] Caveolin-1 is involved in reactive oxygen species-induced SHP-2 activation in astrocytes
  • 일반논문[20110901] The ageing systemic milieu negatively regulates neurogenesis and cognitive function
  • 일반논문[20110201] Development of Complete Thoracic Spinal Cord Transection Model in Rats for Delayed Transplantation of Stem Cells
  • 일반논문[20100916] The effect of mesenchymal stem cell transplantation on the recovery of bladder and hindlimb function after spinal cord contusion in rats
  • 일반논문[20100501] Evacuated Calcium Phosphate Spherical Microcarriers for Bone Regeneration
  • 일반논문[20100401] Differential alternative splicing of human transglutaminase 4 in benign prostate hyperplasia and prostate cancer
  • 일반논문[20091001] Serial Changes in Bladder, Locomotion, and Levels of Neurotrophic Factors in Rats with Spinal Cord Contusion
  • 일반논문[20081220] The amount of 8.4% sodium bicarbonate needed to neutralize the acidity of rocuronium so as to prevent injection pain
  • 일반논문[20081201] Selective COX-2 inhibitors modulate cellular senescence in human dermal fibroblasts in a catalytic activity-independent manner.
  • 일반논문[20081001] Adipose-Derived Stem Cells and Their Secretory Factors as a Promising Therapy for Skin Aging.
  • 일반논문[20080731] BMI-1026 treatment can induce SAHF formation by activation of Erk1/2
  • 일반논문[20080401] Whitening effect of adipose-derived stem cells: A critical role of TGF-b1
  • 일반논문[20080201] Evidence supporting antioxidant action of adipose-derived stem cells: Protection of human dermal fibroblasts from oxidative stress.
  • 일반논문[20071103] 노화된 사람 섬유아세포에의 효율적 유전자 이입방법 개발
  • 일반논문[20071001] Wound healing effect of adipose-derived stem cells: A critical role of secretory factors on human dermal fibroblasts.
  • 일반논문[20050501] Increased caveolin-1, a cause for the declined adipogenic potential of senescent human mesenchymal stem cells
  • 일반논문[20041231] βPAK-interacting exchange factor may regulate actin cytoskeleton through interaction with actin
  • 일반논문[20040331] 세포노화, 세포자연사, 발암(Cellular Senescence, Apoptosis and Carcinogenesis)
  • 일반논문[20030725] Senescent phenotype can be reversed by reduction of caveolin status
  • 일반논문[20030321] Altered cAMP signaling induced by lysophosphatidic acid in senescent human diploid fibroblasts.
  • 저서/역서[20130320] 의학생화학 3판
  • 저서/역서[20060820] 레닌저 생화학 상/하
  • 저서/역서[20060410] 최신의과학용어사전
  • 저서/역서[20050201] 리핀코트의 그림으로 보는 생화학
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