한규동 사진

한규동 | 의과대학 의예과

  • 직급:
    부교수

소개

단국대학교 미생물학과를 졸업한 후, 동대학원에서 손승렬 교수님의 지도하에 Phenanthrene을 분해하는 Sphingomonas의 특성과 계통 유전학적 연구로 석사학위를 하였고, 미국 바톤루지에 있는 Louisiana State University 생물학과에서 Dr. Batzer의 지도하에 인간과 침팬지 종에서 레트로트렌스포존에 의해 유발되는 유전체 유동성에 관한 연구로 3년만에 박사학위를 취득하였습니다. 박사학위 과정 동안 루이지에나 주립대에서 기초생물학실험, 생화학 실험, 그리고 분자 유전학을 가르쳤으며, 2006년 생물학과에서 매년 단 한 명에게만 주어지는 William H. Gates (Teaching Excellence) award를 받았습니다. 동실험실에서 박사 후 연구과정으로 3년 재직하였고, 이 과정동안 두편의 science 논문을 포함해 총 11편의 SCI논문을 발표하였습니다. 이러한 연구성과 때문에 2007년 과학기술부로부터 "미래를 여는 우수 과학자 10인"에 선정되었습니다. 2009년 7월 두번째 박사 후 연구과정으로 텍사스 어스틴 대학에 분자 유전학/미생물학과 Dr. Sawyer lab에 합류하였고, 이곳에선 레트로바이러스들에 의해 감염된 세포의 세포질에서 레트로바이러스의 감염을 저해하는 유전자와 단백질을 연구하였습니다.

학력

  • [2000] 학사 단국대학교(천안캠퍼스) 미생물학
  • [2002] 석사 단국대학교(천안캠퍼스) 미생물학 미생물학
  • [2006] 박사 Louisiana State Univ. Agricultural and Mechanical College 생물학과 생물정보학

주요경력

  • Louisiana State University (2006-08-01)
  • University of Texas Austin (2009-07-01)

주요연구분야

레트로트렌스포존에 의한 인간 및 영장류 유전체의 불안정성
레트로트렌스포존을 이용한 계통 분석학
비교 유전체학과 군집 유전학
영장류 유전체 진화
Next-Generation Sequencing (Whole genome sequencing, Exome sequencing, transcriptome, and Metagenomics)

컨설팅 가능 분야

유전자 마커 개발
레트로트렌스포존에 관련된 질병 탐지
생물정보학 프로그램 개발

연구업적

  • 일반논문[20171001] Structural variations generated by simian foamy virus-like (SFV) in Crocodylus siamensis
  • 일반논문[20170901] The Whole-Genome and Transcriptome of the Manila Clam (Ruditapes philippinarum)
  • 일반논문[20170401] Whole-exome sequencing in Tricho-rhino-phalangeal syndrome (TRPS) type I in a Korean family
  • 일반논문[20170101] Chicken (Gallus gallus) endogenous retrovirus generates genomic variations in the chicken genome
  • 일반논문[20161201] Modulation of LINE-1 Retrotransposition by a Human SAMHD1 Polymorphism
  • 일반논문[20161001] An adaptive detection method for fetal chromosomal aneuploidy using cell-free DNA from 447 Korean women
  • 일반논문[20160901] Structural Variation of Alu Element and Human Disease
  • 일반논문[20160901] Mutational Analysis of Extranodal NK/T-Cell Lymphoma Using Targeted Sequencing with a Comprehensive Cancer Panel
  • 일반논문[20160801] A Genome-Wide Methylation Approach Identifies a New Hypermethylated Gene Panel in Ulcerative Colitis
  • 일반논문[20160501] Comparison of two high-throughput semiconductor chip sequencing platforms in noninvasive prenatal testing for Down syndrome in early pregnancy
  • 일반논문[20160201] Relationship between Single Nucleotide Polymorphisms in the Peroxisome Proliferator-Activated Receptor Gamma Gene and Fatty Acid Composition in Korean Native Cattle
  • 일반논문[20160201] Whole Genome Re-sequencing of Three Domesticated Chicken Breeds
  • 일반논문[20160101] Analysis of L1-chimeric transcripts derived from bidirectional promoter of human-specific L1
  • 일반논문[20151201] Gene structure variation in segmental duplication block C of human chromosome 7q 11.23 during primate evolution
  • 일반논문[20151201] identification of transposable element-mediated deletions in 27 korean individuals based on whole genome sequencing data
  • 일반논문[20151101] Dynamic changes in host gene expression associated with H5N8 avian influenza virus infection in mice
  • 일반논문[20151001] The first whole genome and transcriptome of the cinereous vulture reveals adaptation in the gastric and immune defense systems and possible convergent evolution between the Old and New World vultures
  • 일반논문[20150901] Identification and expression analysis of human endogenous retrovirus Y (HERV-Y) in various human tissues
  • 일반논문[20150701] Meeting report: The biology of genomes and proteomes
  • 일반논문[20150501] Simple method for markerless 1 gene deletion of multidrug-resistant Acinetobacter baumannii
  • 일반논문[20150501] Genome-wide target site triplication of Alu elements in the human genome
  • 일반논문[20150301] Endogenous retrovirus-mediated genomic variations in chimpanzees
  • 일반논문[20150301] An automated analysis pipeline for a large set of ChIP-seq data: AutoChIP
  • 일반논문[20150301] Genome-Wide Analysis of DNA Methylation before-and after Exercise in the Thoroughbred Horse with MeDIP-Seq
  • 일반논문[20150201] Evolutionary fate of SVA2 elements in primate genomes
  • 일반논문[20150101] Transposable element-driven transcript diversification and its relevance to genetic disorders
  • 일반논문[20150101] Identification of human-specific AluS element through comparative genomics
  • 일반논문[20150101] TE composition of human long noncoding RNAs and their expression patterns in human tissues
  • 일반논문[20141201] Whole genome sequence and analysis of the Marwari horse breed and its genetic origin
  • 일반논문[20141001] Comparative study of different molecular methods for typing of Acinetobacter baumannii clinical isolates from University Hospitals
  • 일반논문[20140801] Genome-wide copy number variants analysis identifies deletion variants associated with ankylosing spondylitis
  • 일반논문[20140715] Genome-Wide Analysis of DNA Methylation in the Thoroughbred Horse
  • 일반논문[20140702] Chimpanzee-Specific Endogenous Retrovirus Generates Genomic Variations in the Chimpanzee Genome
  • 일반논문[20140701] Mucilaginibacter koreensis sp. nov., isolated from leaf mold
  • 일반논문[20140518] BLAT-based Comparative Analysis for Transposable Elements: BLATCAT
  • 일반논문[20131230] Phylogeny of Flavobacteria Group Isolated from Freshwater Using Multilocus Sequencing Analysis
  • 일반논문[20131001] Meeting report: Frontiers in genetics: genomics and epigenomics
  • 일반논문[20130930] Septicemia Caused by Leuconostoc lactis with Intrinsic Resistance to Vancomycin in a Patient with Biliary Stent
  • 일반논문[20130801] Identification and characterization of transposable elements inserted into the coding sequences of horse genes
  • 일반논문[20130603] DNA methylation of mobile genetic elements in human cancers
  • 일반논문[20130601] Coexistence of blaOXA-23 and armA in multidrug-resistant Acinetobacter baumannii isolated from hospital in South Korea
  • 일반논문[20130412] Human-specific HERV-K insertion causes genomic variations in the human genome
  • 일반논문[20130110] The novel MER transposon-derived miRNAs in human genome
  • 일반논문[20121230] Transposable Elements: No More ‘Junk DNA’
  • 일반논문[20121001] Flavobacterium dankookense sp. nov., isolated from a freshwater reservoir and emended descriptions of Flavobacterium cheonanense, F. chungnamense, F. Koreenes and F. aquatile
  • 일반논문[20120827] mRNA sequence analysis and quantitative expression of the ADAMTS4 gene in the thoroughbred horse
  • 일반논문[20120518] Human Genomic Deletions Generated by SVA-Associated Events
  • 일반논문[20120501] UniPrimer: A Web-Based Primer Design Tool for Comparative Analyses of Primate Genomes
  • 일반논문[20120427] Arenimonas aquaticum sp. nov., a member of the grammaproteobacterium, isolated from a freshwater reservoir
  • 일반논문[20120401] First case of Nocardia nova spinal abscess in an immunocompetent patient
  • 일반논문[20120401] In vitro CpG methylation and garcinol reduce PERV LTR promoter activity
  • 일반논문[20120315] Identification of ORF sequences and exercise-induced expression change in thoroughbred horse OXCT1 gene
  • 일반논문[20120207] High Levels of Sequence Diversity in the 5 UTRs of Human-Specific L1 Elements
  • 일반논문[20111229] Evolutionary diversification of DYX1C1 transcripts via an HERV-H LTR integration event
  • 일반논문[20111201] Development of GEBRET: a web-based analysis tool for retroelements in primate genomes
  • 일반논문[20111201] Quantitative analysis of transcript variants of CHM gene containing LTR12C element in humans
  • 일반논문[20111201] Identification of a Genomic Reservoir for New TRIM Genes in Primate Genomes
  • 일반논문[20111001] A vertically stacked, polymer, microfluidic point mutation analyzer: Rapid high accuracy detection of low-abundance K-ras mutations
  • 일반논문[20111001] Transcriptional variations mediated by an alternative promoter of the FPR3 gene
  • 일반논문[20110923] Alu pair exclusions in the human genome
  • 일반논문[20110801] Quantitative analysis of the HERV pol gene in human tissues
  • 일반논문[20110630] Characterization of Acinetobacter baumannii Co-producing Carbapenemases OXA-23 and OXA-66, and armA 16S Ribosomal RNA Methylase at a University Hospital in South Korea
  • 일반논문[20110401] Genomic Structure and Expression Analyses of the PYGM Gene in the Thoroughbred Horse
  • 지식재산권[20161206] 자살벡터를 이용하여 다제내성 균주의 변이주를 제작하는 방법(Process for preparing murtant strain of multidrug-resistant strain using suicide vector)
  • 지식재산권[20161012] 비교유전체 방법을 이용한 재래닭, 청계, 레그호온 품종 판별용 분자 마커 조성물
  • 지식재산권[20160705] 다제내성 균주의 변이주 제작용 자살벡터
  • 지식재산권[20140901] 자살벡터를 이용하여 다제내성 균주의 변이주를 제작하는 방법
  • 지식재산권[20140901] 다제내성 균주의 변이주 제작용 자살벡터
  • 학술발표[20161111] Chicken (Gallus gallus) Endogenous Retrovirus Generates Genomic Variations in the Chicken Genome
  • 학술발표[20161110] Novel Mutation Candidates in Tricho-rhino-phalangeal syndrome type I (TRPS) Based on the Korean Familial Whole Exome Sequencing Analysis
  • 학술발표[20161110] Identification and Functional Analysis of TSH Receptor Mutations in Pediatric Patients with Congenital Hypothyroidism
  • 학술발표[20161012] Transposable Element-Associated Structure Variations (TAsVs) in the Korean Genome
  • 학술발표[20160616] Transposable elements-associated structure variation from Korean genome
  • 학술발표[20151205] A Step for the Completion of Korean Reference Genome and Identification of Transposable Elements-Associated Structure Variation (TASVs)
  • 학술발표[20151204] Analysis of L1-Chimeric Transcripts Derived from Bidirectional Promoter of Human-Specific L1
  • 학술발표[20151204] Chicken (Gallus gallus) Endogenous Retrovirus Generated Genomic Variation within Different Chicken Species
  • 학술발표[20151204] Identification of Transposable element-Mediated Deletions in 27 Korean Individuals Based on Whole Genome Sequencing Data
  • 학술발표[20151204] Family-Based Whole-Exome Sequencing (WES) Analysis of Tricho-Rhino-Phalangeal Syndrome (TRPS) Patient
  • 학술발표[20151204] Novel Mutation of TSHR in Pediatric Thyroid Disease
  • 학술발표[20150531] Simple method for makerless gene deletion of multidrug-resistant Acinetobacter baumannii
  • 학술발표[20140516] Evolution fate of SVA2 elements in the primate genomes
  • 학술발표[20140516] Long noncoding RNAs with transposable elements in human: Analysis of structure and expression
  • 학술발표[20140515] Chicken (Gallus Gallus) Endogenous Retrovirus Generates Genomic Variations in the Chicken Genome
  • 학술발표[20140331] What happens if old retrotransposons are still active?
  • 학술발표[20131026] Evolutionary fate of species-specific endogenous retroviruses (ERVs) in the human and chimpanzee lineages
  • 학술발표[20131011] Contribution of Human-Specific LINE-1 to the Human Transcriptome Diversification
  • 학술발표[20131011] Identification of Human-Specific AluS elements and their polymorphism among population
  • 학술발표[20130905] Evolutionary Fate of Species-Specific Endogenous Retroviruses (ERVs) in the Human and Chimpanzee Lineages
  • 학술발표[20130905] Identification of Human-Specific AluS: Various Evolutionary Pattern and Polymorphism among Populations
  • 학술발표[20130905] Contribution of Human-Specific LINE-1 to the Human Transcriptome Diversification
  • 학술발표[20130905] Structure and Expression of the Human Long Noncoding RNAs by Transposable Elements
  • 학술발표[20130905] Bioinformatic Analysis of SVA2 Element in Primate Genome through Establishment of Novel Consensus Sequences
  • 학술발표[20130628] Evolutionary fate of species-specific endogenous retroviruses (ERVs) in the human and chimpanzee lineages
  • 학술발표[20130628] Identification of human-specific AluS elements through comparing with ohter non-human primates
  • 학술발표[20130611] Endogenous retroviruses creates genomics variation between the human and chimpanzee lineages
  • 학술발표[20130426] Human-specific HERV-K insertion causes genomic variations in the human genome
  • 학술발표[20130204] Genome-Wide Target Site Triplication of Alu Elements in the Human Genome
  • 학술발표[20121012] Chimpanzee-Specific Endogenous Retroviruses (PtERVs) Generate Structural Genomic Variation in the Chimpanzee Genome
  • 학술발표[20121012] Human-Specific HERV-K Insertion Causes Genomic Variation in the Human Genome
  • 학술발표[20121010] Mobile Elements; No More 'Junk DNA'
  • 학술발표[20120913] Identification of Novel SVA2 in Human Genome through Comparative Genomics
  • 학술발표[20120913] Identification of Chimpanzee-Specific Endogenous Retrovirus through Comparative Genomics
  • 학술발표[20120706] Human-specific insertions of human endogenous retrovirus K (HERV-K) create structural variation in the human genome
  • 학술발표[20120503] Multi-locus Sequence Analysis of the Genus Flavobacterium Based on Genetic Diagnosis
  • 학술발표[20120503] Multi-locus Sequence Analysis for Identification of Acinetobacter Species
  • 학술발표[20111028] Retrotransposon Mediated Genomic Variation in the Human Lineage
  • 학술발표[20110818] Genome-wide target site triplication of Alu elements in the human genome
  • 학술발표[20110808] Human-specific insertions of human endogenous retrovirus K (HERV-K) create structural variation in the human genome
  • 학술발표[20110512] The 5'UTR Analysis of Human-Specific LINE-1
캠퍼스별 교무팀